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VERTEX PHARMACEUTICALS

VRTX

Holders

2

Combined Value

$206.33M

Combined Shares

462,075

Current Price

$444.93

52W High

$507.92

vs 52W High

−12.4%

Investor Activity Chart

Quarterly buys (▲) and sells (▼) by tracked investors. Click a marker to view that investor's portfolio; hover for details. Price line is implied from 13F filings (value ÷ shares), not market data.

$373.00$416.49$459.97$503.46Q2'24Q3'24Q4'24Q1'25Q2'25Q3'25Q4'25Q1'26Q2 2024 · implied price $468.72Q3 2024 · implied price $465.08Q4 2024 · implied price $402.70Q1 2025 · implied price $484.82Q2 2025 · implied price $445.20Q3 2025 · implied price $391.64Q4 2025 · implied price $453.36Q1 2026 · implied price $446.54Jim Simons - Renaissance Technologies · bought 1,566,388 shares @ ~$468.72 · Q2 2024 (new position)Tweedy, Browne Company · bought 54,346 shares @ ~$468.72 · Q2 2024 (new position)Jim Simons - Renaissance Technologies · bought 65,105 shares @ ~$465.08 · Q3 2024Tweedy, Browne Company · sold 746 shares @ ~$465.08 · Q3 2024Jim Simons - Renaissance Technologies · sold 234,284 shares @ ~$402.70 · Q4 2024Tweedy, Browne Company · sold 12,969 shares @ ~$402.70 · Q4 2024Jim Simons - Renaissance Technologies · sold 225,638 shares @ ~$484.82 · Q1 2025Tweedy, Browne Company · sold 2,315 shares @ ~$484.82 · Q1 2025Jim Simons - Renaissance Technologies · sold 166,683 shares @ ~$445.20 · Q2 2025Tweedy, Browne Company · sold 1,063 shares @ ~$445.20 · Q2 2025Tweedy, Browne Company · bought 1,812 shares @ ~$391.64 · Q3 2025Jim Simons - Renaissance Technologies · sold 269,000 shares @ ~$391.64 · Q3 2025Tweedy, Browne Company · bought 83 shares @ ~$453.36 · Q4 2025Jim Simons - Renaissance Technologies · sold 230,840 shares @ ~$453.36 · Q4 2025Tweedy, Browne Company · bought 1,239 shares @ ~$446.54 · Q1 2026Jim Simons - Renaissance Technologies · sold 83,360 shares @ ~$446.54 · Q1 2026BUYSELLIMPLIED PRICE

Held By

Tracked investors currently holding this security, based on each investor's most recent 13F filing. Gain compares the current market price to each investor's estimated average buy price.

InvestorValue% of PortfolioAvg Buy PriceGainLast ActivityAs of
Jim Simons - Renaissance Technologies$188.30M0.29%~$468.57−5.0%SELL Q1 2026Q1 2026
Tweedy, Browne Company$18.03M1.43%~$464.55−4.2%BUY Q1 2026Q1 2026

Recent Activity

Latest position changes by tracked investors. Prices are estimates implied from 13F filings.

QuarterInvestorActionEst. ValueEst. Price
Q1 2026Jim Simons - Renaissance TechnologiesSELL−$37.22M~$446.54
Q1 2026Tweedy, Browne CompanyBUY+$553.3K~$446.54
Q4 2025Jim Simons - Renaissance TechnologiesSELL−$104.65M~$453.36
Q4 2025Tweedy, Browne CompanyBUY+$37.6K~$453.36
Q3 2025Jim Simons - Renaissance TechnologiesSELL−$105.35M~$391.64
Q3 2025Tweedy, Browne CompanyBUY+$709.7K~$391.64
Q2 2025Jim Simons - Renaissance TechnologiesSELL−$74.21M~$445.20
Q2 2025Tweedy, Browne CompanySELL−$473.2K~$445.20
Q1 2025Jim Simons - Renaissance TechnologiesSELL−$109.39M~$484.82
Q1 2025Tweedy, Browne CompanySELL−$1.12M~$484.82
Q4 2024Jim Simons - Renaissance TechnologiesSELL−$94.35M~$402.70
Q4 2024Tweedy, Browne CompanySELL−$5.22M~$402.70
Q3 2024Jim Simons - Renaissance TechnologiesBUY+$30.28M~$465.08
Q3 2024Tweedy, Browne CompanySELL−$346.9K~$465.08
Q2 2024Jim Simons - Renaissance TechnologiesNEW BUY+$734.20M~$468.72
Q2 2024Tweedy, Browne CompanyNEW BUY+$25.47M~$468.72

Ownership History

Aggregate position across all tracked investors per quarter (options excluded). Implied price is the reported value divided by shares held.

PeriodHoldersTotal SharesΔ SharesTotal ValueImplied Price
Q1 20262462,075-15.1%$206.33M$446.54
Q4 20252544,196-29.8%$246.72M$453.36
Q3 20252774,953-25.6%$303.50M$391.64
Q2 202521,042,141-13.9%$463.96M$445.20
Q1 202521,209,887-15.9%$586.58M$484.82
Q4 202421,437,840-14.7%$579.02M$402.70
Q3 202421,685,093+4.0%$783.70M$465.08
Q2 202421,620,734$759.67M$468.72